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ea0099p261 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Familial partial lipodystrophy:genetic and clinical data from a greek referral center

Kountouri Aikaterini , Korakas Emmanouil , Maratou Eirini , Ikonomidis Ignatios , Balampanis Konstantinos , Pliouta Loukia , Liatis Stavros , Tentolouris Nikolaos , Toulas Panagiotis , Kousathana Foteini , Giatzakis Christoforos , Dimitriadis George , Lambadiari Vaia

Background: Familial partial lipodystrophy (FPLD) is a rare syndrome in which a patients phenotype is not dependent merely on the specific genetic mutation, but also on a combination of other demographic, environmental and genetic factors. In this report, we present a large cohort of novel mutation in FPLD patients from a large referral center in Greece and we investigate the possible relationship between the genetic variations detected and their phenotype and the effect...

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ea0099p292 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

The effect of ketogenic diet versus mediterranean diet on clinical and biochemical markers of inflammation in patients with obesity and psoriatic arthritis

Kountouri Aikaterini , Katsimbri Pelagia , Korakas Emmanouil , Pliouta Loukia , Agapitou Vasileia , Maratou Eirini , Pavlidis George , Ikonomidis Ignatios , Papathanasi Argyro , Malisova Sofia , Vlachos Dionysios , Papadavid Evangelia , Lambadiari Vaia

Background: Obesity is over-represented in patients with psoriasis (PSO) and psoriatic arthritis (PsA) and associated with higher disease activity and poorer treatment response. A substantial number of studies have highlighted the beneficial effect of weight loss in PSO and PsA disease activity. However, the data regarding the most efficacious diet pattern are scarce. The aim of our study to evaluate the effectiveness of Mediterranean diet (MD) and Ketogenic diet (KD), in pati...

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ea0099p464 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Combined dulaglutide-dapagliflozin treatment improves vascular dysfunction and albuminuria vs DPP4 inhibitors independently of glycaemic control

Korakas Emmanouil , Ikonomidis Ignatios , Thymis John , Kountouri Aikaterini , Pliouta Loukia , Katogiannis Konstantinos , Benas Dimitris , Balampanis Konstantinos , Prentza Vasiliki , Kousathana Foteini , Kostelli Gavriela , Dimitriadis George , Raptis Athanasios , Lambadiari Vaia

Background: The association between diabetes mellitus and diabetic nephropathy with vascular and endothelial properties is well-established. In this study, we compared the effect of combined treatment with dulaglutide and dapagliflozin versus DPP-4 inhibitors on endothelial glycocalyx, arterial stiffness, myocardial function and albuminuria in patients with type 2 diabetes mellitus and albuminuria.Methods: A total of 60 patients with type 2 diabetes mell...

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Endocrine Abstracts

Familial partial lipodystrophy:genetic and clinical data from a greek referral center

The effect of ketogenic diet versus mediterranean diet on clinical and biochemical markers of inflammation in patients with obesity and psoriatic arthritis

Combined dulaglutide-dapagliflozin treatment improves vascular dysfunction and albuminuria vs DPP4 inhibitors independently of glycaemic control

BiosciAbstracts